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Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours.
Nwosu ZC, Battello N, Rothley M, Piorońska W, Sitek B, Ebert MP, Hofmann U, Sleeman J, Wölfl S, Meyer C, Megger DA, Dooley S. Nwosu ZC, et al. J Exp Clin Cancer Res. 2018 Sep 3;37(1):211. doi: 10.1186/s13046-018-0872-6. J Exp Clin Cancer Res. 2018. PMID: 30176945 Free PMC article.
BACKGROUND: Although metabolism is profoundly altered in human liver cancer, the extent to which experimental models, e.g. cell lines, mimic those alterations is unresolved. ...ACAA1/2, ACADSB, HADH), urea cycle (e.g. CPS1, ARG1, ASL), molecule transport (e.g …
BACKGROUND: Although metabolism is profoundly altered in human liver cancer, the extent to which experimental models, e.g. cel …
Identification of hepatocellular carcinoma-associated hub genes and pathways by integrated microarray analysis.
Liu F, Li H, Chang H, Wang J, Lu J. Liu F, et al. Tumori. 2015 Mar-Apr;101(2):206-14. doi: 10.5301/tj.5000241. Epub 2015 Mar 13. Tumori. 2015. PMID: 25768320
The protein-protein interaction network indicated that CDH1, ECHS1, ACAA1, MT2A, and MYC were important genes which participated in many interactions. Experimental validation of the role of four upregulated genes (ECHS1, ACAA1, MT2A and MYC) in the progressio …
The protein-protein interaction network indicated that CDH1, ECHS1, ACAA1, MT2A, and MYC were important genes which participated in m …